psf-1 putative DNA replication complex GINS protein PSF1 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: psf-1
Official Full Name: putative DNA replication complex GINS protein PSF1
Primary source: WormBase:WBGene00011275
Locus tag: CELE_R53.6
See related: AllianceGenome:WB:WBGene00011275
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in DNA strand elongation involved in mitotic DNA replication. Predicted to be located in nucleus. Predicted to be part of GINS complex. Human ortholog(s) of this gene implicated in immunodeficiency 55. Orthologous to human GINS1 (GINS complex subunit 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See psf-1 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 6

Sequence:: Chromosome: II; NC_003280.10 (9968673..9969630)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

R53.4 (e-PCR)
- UniSTS:321029

R53.6 (e-PCR)
- UniSTS:317020

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in DNA replication	IEA Inferred from Electronic Annotation more info
involved_in DNA strand elongation involved in mitotic DNA replication	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of GINS complex	IBA Inferred from Biological aspect of Ancestor more info
part_of GINS complex	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: putative DNA replication complex GINS protein PSF1

NP_496153.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

9968673..9969630

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_063752.6 → NP_496153.2 putative DNA replication complex GINS protein PSF1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_496153.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q22019

Conserved Domains (2) summary

cd11710
Location:12 → 137

GINS_A_psf1; Alpha-helical domain of GINS complex protein Psf1

COG5230
Location:18 → 200

COG5230; Uncharacterized conserved protein [Function unknown]