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    sna-1 Small Nuclear RNA (snRNA) Associated protein [ Caenorhabditis elegans ]

    Gene ID: 179064, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sna-1
    Official Full Name
    Small Nuclear RNA (snRNA) Associated protein
    Primary source
    WormBase:WBGene00020951
    Locus tag
    CELE_W02F12.6
    See related
    AllianceGenome:WB:WBGene00020951
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transcription coactivator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of core mediator complex and mediator complex. Is expressed widely. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See sna-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (6709578..6710679, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene Serpentine receptor class gamma-30

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel family of C. elegans snRNPs contains proteins associated with trans-splicing. MacMorris M, et al. RNA, 2007 Apr. PMID 17283210, Free PMC Article
    2. An in vivo genetic screen for genes involved in spliced leader trans-splicing indicates a crucial role for continuous de novo spliced leader RNP assembly. Philippe L, et al. Nucleic Acids Res, 2017 Aug 21. PMID 28582530, Free PMC Article
    3. A novel, essential trans-splicing protein connects the nematode SL1 snRNP to the CBC-ARS2 complex. Fasimoye RY, et al. Nucleic Acids Res, 2022 Jul 22. PMID 35736244, Free PMC Article
    4. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article
    5. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of core mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Small Nuclear RNA (snRNA) Associated protein
    NP_504701.2
    • Product from WormBase gene class sna;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      6709578..6710679 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072300.7 → NP_504701.2  Small Nuclear RNA (snRNA) Associated protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504701.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45149
    Nucleotide Protein
    Heading Accession and Version

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