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    col-54 Nematode cuticle collagen N-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 185226, updated on 9-Dec-2024

    Summary

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    Official Symbol
    col-54
    Official Full Name
    Nematode cuticle collagen N-terminal domain-containing protein
    Primary source
    WormBase:WBGene00000631
    Locus tag
    CELE_F33D11.3
    See related
    AllianceGenome:WB:WBGene00000631
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of cuticle. Involved in defense response to Gram-negative bacterium. Predicted to be located in membrane. Predicted to be part of collagen trimer. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See col-54 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (5842709..5844050)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Homeobox domain-containing protein;Homeobox protein ceh-12 Neighboring gene ncRNA Neighboring gene tRNA-Arg Neighboring gene DUF4263 domain-containing protein Neighboring gene WH2 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genomic analysis of immune response against Vibrio cholerae hemolysin in Caenorhabditis elegans. Sahu SN, et al. PLoS One, 2012. PMID 22675448, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of cuticle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response to Gram-negative bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of collagen trimer IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nematode cuticle collagen N-terminal domain-containing protein
    NP_491694.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      5842709..5844050
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059293.5 → NP_491694.1  Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491694.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44774
      Conserved Domains (3) summary
      pfam01391
      Location:133 → 191
      Collagen; Collagen triple helix repeat (20 copies)
      smart01088
      Location:6 → 58
      Col_cuticle_N; Nematode cuticle collagen N-terminal domain
      PHA03169
      Location:147 → 262
      PHA03169; hypothetical protein; Provisional
    Nucleotide Protein
    Heading Accession and Version

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