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    DC2.5 DeHydrogenases, Short chain [ Caenorhabditis elegans ]

    Gene ID: 183970, updated on 9-Dec-2024

    Summary

    Official Symbol
    DC2.5
    Official Full Name
    DeHydrogenases, Short chain
    Primary source
    WormBase:WBGene00017082
    Locus tag
    CELE_DC2.5
    See related
    AllianceGenome:WB:WBGene00017082
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable oxidoreductase activity. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; esophagus squamous cell carcinoma; and squamous cell carcinoma. Orthologous to human WWOX (WW domain containing oxidoreductase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See DC2.5 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (210145..212787, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Trafficking protein particle complex subunit Neighboring gene Galectin;Galectin domain-containing protein Neighboring gene Serpentine Receptor, class H Neighboring gene Serpentine Receptor, class H

    General protein information

    Preferred Names
    DeHydrogenases, Short chain
    NP_503155.4
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      210145..212787 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070754.6NP_503155.4  DeHydrogenases, Short chain [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_503155.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9UAW2
      Conserved Domains (1) summary
      cd05327
      Location:45323
      retinol-DH_like_SDR_c_like; retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs

    RNA

    1. NR_132472.1 RNA Sequence

      Status: REVIEWED