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    sprp-4 C2H2-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 181132, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sprp-4
    Official Full Name
    C2H2-type domain-containing protein
    Primary source
    WormBase:WBGene00016189
    Locus tag
    CELE_C28G1.4
    See related
    AllianceGenome:WB:WBGene00016189
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in dorsal nerve cord; nerve ring; and ventral nerve cord. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See sprp-4 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    5
    Sequence:
    Chromosome: X; NC_003284.9 (8849056..8853624, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene tRNA-Gly Neighboring gene E2 ubiquitin-conjugating enzyme Neighboring gene Uncharacterized protein Neighboring gene Neuropeptide-Like Protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
    2. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    C2H2-type domain-containing protein
    NP_509499.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      8849056..8853624 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077098.6 → NP_509499.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509499.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18289
      Conserved Domains (2) summary
      COG5665
      Location:557 → 746
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      sd00017
      Location:803 → 819
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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