slc-25A18.2 SLC (SoLute Carrier) homolog [Caenorhabditis elegans] - Gene

Summary

Official Symbol: slc-25A18.2
Official Full Name: SLC (SoLute Carrier) homolog
Primary source: WormBase:WBGene00018901
Locus tag: CELE_F55G1.5
See related: AllianceGenome:WB:WBGene00018901
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable L-aspartate transmembrane transporter activity and L-glutamate transmembrane transporter activity. Predicted to be involved in L-glutamate transmembrane transport; aspartate transmembrane transport; and malate-aspartate shuttle. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 3. Orthologous to human SLC25A18 (solute carrier family 25 member 18) and SLC25A22 (solute carrier family 25 member 22). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

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Function	Evidence Code	Pubs
enables L-aspartate transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables L-glutamate transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in L-aspartate transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in L-glutamate transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in aspartate transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in malate-aspartate shuttle	IBA Inferred from Biological aspect of Ancestor more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info

NP_501198.1

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The following sections contain reference sequences that belong to a specific genome build. Explain