rab-14 Ras-related protein Rab-14 [Caenorhabditis elegans] - Gene

Summary

Official Symbol: rab-14
Official Full Name: Ras-related protein Rab-14
Primary source: WormBase:WBGene00004276
Locus tag: CELE_K09A9.2
See related: AllianceGenome:WB:WBGene00004276
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable GTPase activity. Involved in phagolysosome assembly involved in apoptotic cell clearance and phagosome acidification involved in apoptotic cell clearance. Located in early endosome; phagocytic vesicle; and trans-Golgi network. Is expressed in gonadal sheath cell; hypodermis; intestine; and pharyngeal muscle cell. Orthologous to human RAB14 (RAB14, member RAS oncogene family). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in Golgi to endosome transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular protein transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in phagolysosome assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in phagolysosome assembly involved in apoptotic cell clearance	IGI Inferred from Genetic Interaction more info	PubMed
involved_in phagolysosome assembly involved in apoptotic cell clearance	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in phagosome acidification involved in apoptotic cell clearance	IGI Inferred from Genetic Interaction more info	PubMed
involved_in phagosome acidification involved in apoptotic cell clearance	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
is_active_in early endosome	IBA Inferred from Biological aspect of Ancestor more info
located_in early endosome	IDA Inferred from Direct Assay more info	PubMed
located_in early endosome membrane	IEA Inferred from Electronic Annotation more info
is_active_in endomembrane system	IBA Inferred from Biological aspect of Ancestor more info
is_active_in phagocytic vesicle	IBA Inferred from Biological aspect of Ancestor more info
located_in phagocytic vesicle	IDA Inferred from Direct Assay more info	PubMed
located_in phagocytic vesicle	IEA Inferred from Electronic Annotation more info
located_in recycling endosome	IEA Inferred from Electronic Annotation more info
located_in trans-Golgi network	IDA Inferred from Direct Assay more info	PubMed

NP_510572.1

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