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    gly-11 Putative polypeptide N-acetylgalactosaminyltransferase 11 [ Caenorhabditis elegans ]

    Gene ID: 176647, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gly-11
    Official Full Name
    Putative polypeptide N-acetylgalactosaminyltransferase 11
    Primary source
    WormBase:WBGene00001636
    Locus tag
    CELE_Y75B8A.9
    See related
    AllianceGenome:WB:WBGene00001636
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable Notch binding activity and polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in protein O-linked glycosylation and regulation of Notch signaling pathway. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Is expressed in excretory cell; hypodermis; and pharyngeal cell. Orthologous to human GALNT11 (polypeptide N-acetylgalactosaminyltransferase 11). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See gly-11 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    7
    Sequence:
    Chromosome: III; NC_003281.10 (12171354..12177245, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene U3 small nucleolar ribonucleoprotein MPP10 Neighboring gene ARC105/Med15 mediator subunit C-terminal domain-containing protein Neighboring gene RING-type domain-containing protein Neighboring gene LURY-1-2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pmr-1 gene affects susceptibility of Caenorhabditis elegans to Staphylococcus aureus infection through glycosylation and stress response pathways' alterations. Schifano E, et al. Virulence, 2019 Dec. PMID 31771413, Free PMC Article
    2. The terminal phase of cytokinesis in the Caenorhabditis elegans early embryo requires protein glycosylation. Wang H, et al. Mol Biol Cell, 2005 Sep. PMID 15987734, Free PMC Article
    3. Predicting PDZ domain-peptide interactions from primary sequences. Chen JR, et al. Nat Biotechnol, 2008 Sep. PMID 18711339, Free PMC Article
    4. Carbohydrates and glycosylation. Berninsone PM. WormBook, 2006 Dec 18. PMID 18050430, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables Notch binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables polypeptide N-acetylgalactosaminyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables polypeptide N-acetylgalactosaminyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein O-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of Notch signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Putative polypeptide N-acetylgalactosaminyltransferase 11
    NP_001022948.1
    • Confirmed by transcript evidence
    NP_001022949.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      12171354..12177245 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001027777.5 → NP_001022948.1  Putative polypeptide N-acetylgalactosaminyltransferase 11 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022948.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7K755, Q9XW72
      Conserved Domains (4) summary
      cd02510
      Location:162 → 461
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      cd00161
      Location:484 → 599
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      pfam00652
      Location:486 → 602
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
      pfam13641
      Location:162 → 392
      Glyco_tranf_2_3; Glycosyltransferase like family 2

    2. NM_001027778.5 → NP_001022949.1  Putative polypeptide N-acetylgalactosaminyltransferase 11 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022949.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7K755
      Conserved Domains (2) summary
      cd02510
      Location:162 → 431
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam13641
      Location:162 → 392
      Glyco_tranf_2_3; Glycosyltransferase like family 2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7K755.2

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