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    tsp-18 TetraSPanin family [ Caenorhabditis elegans ]

    Gene ID: 192068, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tsp-18
    Official Full Name
    TetraSPanin family
    Primary source
    WormBase:WBGene00006644
    Locus tag
    CELE_F59G1.2
    See related
    AllianceGenome:WB:WBGene00006644
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tsp-18 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    7
    Sequence:
    Chromosome: II; NC_003280.10 (5904552..5906385)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene LisH domain-containing protein;VQ domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Vacuolar protein sorting-associated protein 35

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The frataxin-encoding operon of Caenorhabditis elegans shows complex structure and regulation. Vázquez-Manrique RP, et al. Genomics, 2007 Mar. PMID 17174523
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    TetraSPanin family
    NP_495178.1
    • Product from WormBase gene class tsp;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      5904552..5906385
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062777.2 → NP_495178.1  TetraSPanin family [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495178.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21052
      Conserved Domains (3) summary
      cd03156
      Location:121 → 247
      uroplakin_I_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), uroplakin_I_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
      pfam00335
      Location:13 → 275
      Tetraspannin; Tetraspanin family
      pfam14897
      Location:11 → 154
      EpsG; EpsG family
    Nucleotide Protein
    Heading Accession and Version

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