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    cdc-50.B Cell cycle control protein 50A [ Caenorhabditis elegans ]

    Gene ID: 184717, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cdc-50.B
    Official Full Name
    Cell cycle control protein 50A
    Primary source
    WormBase:WBGene00008969
    Locus tag
    CELE_F20C5.4
    See related
    AllianceGenome:WB:WBGene00008969
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in innate immune response. Predicted to be located in membrane. Predicted to be active in Golgi apparatus; endoplasmic reticulum; and plasma membrane. Orthologous to human TMEM30B (transmembrane protein 30B). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cdc-50.B in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    7
    Sequence:
    Chromosome: IV; NC_003282.8 (8764867..8767447)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Enlarged germline granules protein 1 Neighboring gene Uncharacterized protein Neighboring gene Kinesin-like protein Neighboring gene ncRNA Neighboring gene PACT_coil_coil domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Extracellular vesicle budding is inhibited by redundant regulators of TAT-5 flippase localization and phospholipid asymmetry. Beer KB, et al. Proc Natl Acad Sci U S A, 2018 Feb 6. PMID 29367422, Free PMC Article
    2. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Shapira M, et al. Proc Natl Acad Sci U S A, 2006 Sep 19. PMID 16968778, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in innate immune response HEP PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Cell cycle control protein 50A
    NP_501511.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      8764867..8767447
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069110.5 → NP_501511.1  Cell cycle control protein 50A [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501511.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19635
      Conserved Domains (1) summary
      pfam03381
      Location:67 → 353
      CDC50; LEM3 (ligand-effect modulator 3) family / CDC50 family
    Nucleotide Protein
    Heading Accession and Version

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