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    sec-31 WD_REPEATS_REGION domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178060, updated on 9-Dec-2024

    Summary

    Official Symbol
    sec-31
    Official Full Name
    WD_REPEATS_REGION domain-containing protein
    Primary source
    WormBase:WBGene00011338
    Locus tag
    CELE_T01G1.3
    See related
    AllianceGenome:WB:WBGene00011338
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable structural molecule activity. Predicted to be involved in COPII-coated vesicle cargo loading and endoplasmic reticulum organization. Predicted to be located in endoplasmic reticulum. Predicted to be part of COPII vesicle coat. Predicted to be active in endoplasmic reticulum exit site. Human ortholog(s) of this gene implicated in Halperin-Birk syndrome. Orthologous to several human genes including SEC31A (SEC31 homolog A, COPII coat complex component). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See sec-31 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    16
    Sequence:
    Chromosome: IV; NC_003282.8 (11365621..11371792, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene tRNA Neighboring gene tRNA Neighboring gene Chitin-binding domain protein cbd-1 Neighboring gene F-box domain-containing protein

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural molecule activity  
    Component Evidence Code Pubs
    part_of COPII vesicle coat  
    located_in endoplasmic reticulum  
    is_active_in endoplasmic reticulum exit site  

    General protein information

    Preferred Names
    WD_REPEATS_REGION domain-containing protein
    NP_502144.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      11365621..11371792 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069743.7NP_502144.1  WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502144.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EFY6
      Conserved Domains (3) summary
      sd00039
      Location:71119
      7WD40; WD40 repeat [structural motif]
      pfam03154
      Location:773895
      Atrophin-1; Atrophin-1 family
      cl29593
      Location:72311
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
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