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    dec-7 Uncharacterized protein [ Caenorhabditis elegans ]

    Gene ID: 176404, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dec-7
    Official Full Name
    Uncharacterized protein
    Primary source
    WormBase:WBGene00010540
    Locus tag
    CELE_K03H1.5
    See related
    AllianceGenome:WB:WBGene00010540
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable cell adhesion mediator activity. Involved in negative regulation of defecation rhythm. Located in apical junction complex. Is expressed in intestine. Orthologous to human SUSD2 (sushi domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See dec-7 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    16
    Sequence:
    Chromosome: III; NC_003281.10 (9932398..9939704)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Transthyretin-like protein 2 Neighboring gene Transthyretin-like protein 1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Ovule protein Neighboring gene Wsv008 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DEC-7/SUSD2, a sushi domain-containing protein, regulates an ultradian behavior mediated by intestinal epithelial Ca(2+) oscillations in Caenorhabditis elegans. Laboy JT, et al. Am J Physiol Cell Physiol, 2023 May 1. PMID 37067458, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables cell adhesion mediator activity IC
    Inferred by Curator
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell-cell adhesion via plasma-membrane adhesion molecules IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of defecation rhythm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apical junction complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Uncharacterized protein
    NP_499205.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      9932398..9939704
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066804.6 → NP_499205.1  Uncharacterized protein CELE_K03H1.5 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499205.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34501
      Conserved Domains (6) summary
      smart00723
      Location:681 → 840
      AMOP; Adhesion-associated domain present in MUC4 and other proteins
      cd00033
      Location:1181 → 1230
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
      smart00429
      Location:468 → 527
      IPT; ig-like, plexins, transcription factors
      smart00539
      Location:286 → 452
      NIDO; Extracellular domain of unknown function in nidogen (entactin) and hypothetical proteins
      pfam10146
      Location:1270 → 1371
      zf-C4H2; Zinc finger-containing protein
      cl02516
      Location:855 → 1055
      VWD; von Willebrand factor type D domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34501.2

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