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    lgc-11 Neur_chan_LBD domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 181009, updated on 9-Dec-2024

    Summary

    Official Symbol
    lgc-11
    Official Full Name
    Neur_chan_LBD domain-containing protein
    Primary source
    WormBase:WBGene00000061
    Locus tag
    CELE_F48E3.7
    See related
    AllianceGenome:WB:WBGene00000061
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in chemical synaptic transmission; monoatomic ion transmembrane transport; and regulation of membrane potential. Predicted to be located in membrane and postsynapse. Predicted to be part of transmembrane transporter complex. Predicted to be active in neuron projection; plasma membrane; and synapse. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See lgc-11 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    10
    Sequence:
    Chromosome: X; NC_003284.9 (7503780..7506633, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene UDP-Glucose Glycoprotein glucosylTransferase Neighboring gene DUF4220 domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-Ala Neighboring gene ncRNA Neighboring gene EGF-like domain-containing protein;Peritrophic membrane chitin binding protein

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in excitatory postsynaptic potential IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in monoatomic ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of membrane potential IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of postsynaptic membrane potential IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in postsynapse IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of transmembrane transporter complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Neur_chan_LBD domain-containing protein
    NP_509270.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      7503780..7506633 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076869.6NP_509270.1  Neur_chan_LBD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509270.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EGR1
      Conserved Domains (2) summary
      pfam02931
      Location:36242
      Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
      pfam02932
      Location:249336
      Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region