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    rack-1 Small ribosomal subunit protein RACK1 [ Caenorhabditis elegans ]

    Gene ID: 177895, updated on 9-Dec-2024

    Summary

    Official Symbol
    rack-1
    Official Full Name
    Small ribosomal subunit protein RACK1
    Primary source
    WormBase:WBGene00010556
    Locus tag
    CELE_K04D7.1
    See related
    AllianceGenome:WB:WBGene00010556
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein kinase C binding activity and ribosome binding activity. Involved in several processes, including antifungal innate immune response; cytoskeleton-dependent cytokinesis; and motor neuron axon guidance. Located in several cellular components, including centrosome; growth cone; and kinetochore. Is expressed in anterior distal tip cell; neurons; and posterior distal tip cell. Orthologous to human RACK1 (receptor for activated C kinase 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See rack-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    4
    Sequence:
    Chromosome: IV; NC_003282.8 (10176680..10177875)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Mitochondrial sorting homolog Neighboring gene putative 4-aminobutyrate aminotransferase, mitochondrial Neighboring gene Tyrosine-protein phosphatase 4

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase C binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ribosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ribosome binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables translation regulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in centrosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in growth cone IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in kinetochore IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Small ribosomal subunit protein RACK1
    NP_501859.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      10176680..10177875
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069458.7NP_501859.1  Small ribosomal subunit protein RACK1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501859.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q21215
      Conserved Domains (3) summary
      COG2319
      Location:2317
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:8318
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:73109
      7WD40; WD40 repeat [structural motif]