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    ceh-41 Homeobox domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180503, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ceh-41
    Official Full Name
    Homeobox domain-containing protein
    Primary source
    WormBase:WBGene00000462
    Locus tag
    CELE_T26C11.5
    See related
    AllianceGenome:WB:WBGene00000462
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in body wall musculature; neurons; and somatic nervous system. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ceh-41 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    4
    Sequence:
    Chromosome: X; NC_003284.9 (1846608..1848675, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene CCHC-type domain-containing protein;Zinc finger, CCHC-type Neighboring gene Homeobox protein ceh-21 Neighboring gene Secreted protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A ONECUT homeodomain protein communicates X chromosome dose to specify Caenorhabditis elegans sexual fate by repressing a sex switch gene. Gladden JM, et al. Genetics, 2007 Nov. PMID 17720939, Free PMC Article
    2. Loss and gain of domains during evolution of cut superclass homeobox genes. Bürglin TR, et al. Int J Dev Biol, 2002 Jan. PMID 11902672
    3. Robust regulatory architecture of pan-neuronal gene expression. Leyva-Díaz E, et al. Curr Biol, 2022 Apr 25. PMID 35259341, Free PMC Article
    4. Unique homeobox codes delineate all the neuron classes of C. elegans. Reilly MB, et al. Nature, 2020 Aug. PMID 32814896, Free PMC Article
    5. A 4D single-cell protein atlas of transcription factors delineates spatiotemporal patterning during embryogenesis. Ma X, et al. Nat Methods, 2021 Aug. PMID 34312566

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Homeobox domain-containing protein
    NP_508340.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      1846608..1848675 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_075939.4 → NP_508340.1  Homeobox domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508340.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22810
      Conserved Domains (1) summary
      pfam00046
      Location:217 → 268
      Homeobox; Homeobox domain
    Nucleotide Protein
    Heading Accession and Version

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