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    glb-6 Globin-like protein 6 [ Caenorhabditis elegans ]

    Gene ID: 182780, updated on 9-Dec-2024

    Summary

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    Official Symbol
    glb-6
    Official Full Name
    Globin-like protein 6
    Primary source
    WormBase:WBGene00015969
    Locus tag
    CELE_C18C4.9
    See related
    AllianceGenome:WB:WBGene00015969
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables heme binding activity; iron ion binding activity; and oxygen binding activity. Predicted to be involved in oxygen transport and response to hypoxia. Is expressed in neurons and somatic nervous system. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See glb-6 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    9
    Sequence:
    Chromosome: V; NC_003283.11 (5568184..5570533, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene GRIP domain-containing protein;Golgin-84 Neighboring gene Globin domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure and properties of a bis-histidyl ligated globin from Caenorhabditis elegans. Yoon J, et al. Biochemistry, 2010 Jul 13. PMID 20518498, Free PMC Article
    2. Computational evidence support the hypothesis of neuroglobin also acting as an electron transfer species. Paltrinieri L, et al. J Biol Inorg Chem, 2017 Jun. PMID 28378164
    3. Globins in Caenorhabditis elegans. Tilleman L, et al. IUBMB Life, 2011 Mar. PMID 21445847
    4. Wide diversity in structure and expression profiles among members of the Caenorhabditis elegans globin protein family. Hoogewijs D, et al. BMC Genomics, 2007 Oct 4. PMID 17916248, Free PMC Article
    5. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    NOT enables carbon monoxide binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables heme binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    NOT enables nitric oxide binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables oxygen binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxygen binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables oxygen binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxygen carrier activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxygen carrier activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in oxygen transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in oxygen transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to hypoxia IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Globin-like protein 6
    NP_504469.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      5568184..5570533 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072068.6 → NP_504469.1  Globin-like protein 6 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504469.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q18086
      Conserved Domains (1) summary
      cd01040
      Location:205 → 342
      Mb_like; myoglobin_like; M family globin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q18086.2

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