ads-1 Alkyldihydroxyacetonephosphate synthase [Caenorhabditis elegans] - Gene

Summary

Official Symbol: ads-1
Official Full Name: Alkyldihydroxyacetonephosphate synthase
Primary source: WormBase:WBGene00000081
Locus tag: CELE_Y50D7A.7
See related: AllianceGenome:WB:WBGene00000081
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable FAD binding activity and alkylglycerone-phosphate synthase activity. Predicted to be involved in ether lipid biosynthetic process. Predicted to be active in peroxisome. Is expressed in intestine. Human ortholog(s) of this gene implicated in rhizomelic chondrodysplasia punctata and rhizomelic chondrodysplasia punctata type 3. Orthologous to human AGPS (alkylglycerone phosphate synthase). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables FAD binding	ISS Inferred from Sequence or Structural Similarity more info
enables alkylglycerone-phosphate synthase activity	IBA Inferred from Biological aspect of Ancestor more info
enables alkylglycerone-phosphate synthase activity	IEA Inferred from Electronic Annotation more info
enables alkylglycerone-phosphate synthase activity	ISS Inferred from Sequence or Structural Similarity more info
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables flavin adenine dinucleotide binding	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in ether lipid biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in ether lipid biosynthetic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in lipid biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in lipid biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in lipid metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in peroxisome	IBA Inferred from Biological aspect of Ancestor more info
located_in peroxisome	IEA Inferred from Electronic Annotation more info

NP_497185.1

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The following sections contain reference sequences that belong to a specific genome build. Explain