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    hpo-10 SAC3/GANP/THP3 conserved domain-containing protein;SAC3_GANP domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 175829, updated on 9-Dec-2024

    Summary

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    Official Symbol
    hpo-10
    Official Full Name
    SAC3/GANP/THP3 conserved domain-containing protein;SAC3_GANP domain-containing protein
    Primary source
    WormBase:WBGene00017158
    Locus tag
    CELE_F01F1.1
    See related
    AllianceGenome:WB:WBGene00017158
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be active in nucleus. Is expressed widely. Orthologous to human LENG8 (leukocyte receptor cluster member 8). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See hpo-10 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    8
    Sequence:
    Chromosome: III; NC_003281.10 (5879489..5882430)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Abnormal cell migration protein 21 Neighboring gene ncRNA Neighboring gene COX assembly mitochondrial protein Neighboring gene Uncharacterized protein Neighboring gene ShKT domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. C30F12.4 influences oogenesis, fat metabolism, and lifespan in C. elegans. Wang L, et al. Protein Cell, 2016 Oct. PMID 27638466, Free PMC Article
    2. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    3. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SAC3/GANP/THP3 conserved domain-containing protein;SAC3_GANP domain-containing protein
    NP_001370504.1
    • Confirmed by transcript evidence
    NP_001379733.1
    • Confirmed by transcript evidence
    NP_498274.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      5879489..5882430
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001382886.1 → NP_001370504.1  SAC3_GANP domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95QN0

    2. NM_065873.5 → NP_498274.1  SAC3/GANP/THP3 conserved domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498274.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZ29
      Conserved Domains (1) summary
      pfam03399
      Location:418 → 612
      SAC3_GANP; SAC3/GANP/Nin1/mts3/eIF-3 p25 family

    3. NM_001392113.1 → NP_001379733.1  SAC3/GANP/THP3 conserved domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8I7L2
      Conserved Domains (1) summary
      cl24019
      Location:404 → 620
      CSN8_PSD8_EIF3K; CSN8/PSMD8/EIF3K family
    Nucleotide Protein
    Heading Accession and Version

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