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    glb-3 GLOBIN domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 182348, updated on 9-Dec-2024

    Summary

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    Official Symbol
    glb-3
    Official Full Name
    GLOBIN domain-containing protein
    Primary source
    WormBase:WBGene00007389
    Locus tag
    CELE_C06H2.5
    See related
    AllianceGenome:WB:WBGene00007389
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable oxygen binding activity and oxygen carrier activity. Predicted to be involved in oxygen transport and response to hypoxia. Is expressed in neurons; non-striated muscle; and somatic nervous system. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See glb-3 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (11134596..11140814)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Glucosamine 6-phosphate N-acetyltransferase;N-acetyltransferase domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Folate transporter 1 Neighboring gene F-box domain-containing protein Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. GLB-3: A resilient, cysteine-rich, membrane-tethered globin expressed in the reproductive and nervous system of Caenorhabditis elegans. Hafideddine Z, et al. J Inorg Biochem, 2023 Jan. PMID 36370505
    2. Wide diversity in structure and expression profiles among members of the Caenorhabditis elegans globin protein family. Hoogewijs D, et al. BMC Genomics, 2007 Oct 4. PMID 17916248, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxygen binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxygen binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxygen carrier activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in oxygen transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in response to hypoxia IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    GLOBIN domain-containing protein
    NP_001367199.1
    • Confirmed by transcript evidence
    NP_001367200.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      11134596..11140814
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001380758.2 → NP_001367199.1  GLOBIN domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      B6EU61
      Conserved Domains (1) summary
      cd01040
      Location:42 → 177
      Mb-like; myoglobin-like; M family globin domain

    2. NM_001380757.1 → NP_001367200.1  GLOBIN domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      B6EU62
      Conserved Domains (1) summary
      cd01040
      Location:114 → 249
      Mb-like; myoglobin-like; M family globin domain
    Nucleotide Protein
    Heading Accession and Version

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