U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    mspn-1 Mitochondrial sorting homolog [ Caenorhabditis elegans ]

    Gene ID: 177896, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    mspn-1
    Official Full Name
    Mitochondrial sorting homolog
    Primary source
    WormBase:WBGene00010557
    Locus tag
    CELE_K04D7.2
    See related
    AllianceGenome:WB:WBGene00010557
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in extraction of mislocalized protein from mitochondrial outer membrane. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in hyperekplexia 4. Orthologous to human ATAD1 (ATPase family AAA domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See mspn-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    5
    Sequence:
    Chromosome: IV; NC_003282.8 (10177968..10180301)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Small ribosomal subunit protein RACK1 Neighboring gene putative 4-aminobutyrate aminotransferase, mitochondrial Neighboring gene Tyrosine-protein phosphatase 4 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Msp1 cooperates with the proteasome for extraction of arrested mitochondrial import intermediates. Basch M, et al. Mol Biol Cell, 2020 Apr 1. PMID 32049577, Free PMC Article
    2. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article
    3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in extraction of mislocalized protein from mitochondrial outer membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial outer membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Mitochondrial sorting homolog
    NP_501860.1
    • Confirmed by transcript evidence
    NP_501861.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      10177968..10180301
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069459.9 → NP_501860.1  Mitochondrial sorting homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501860.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P54815, Q95ZR8
      Conserved Domains (2) summary
      smart00382
      Location:116 → 244
      AAA; ATPases associated with a variety of cellular activities
      pfam00004
      Location:120 → 249
      AAA; ATPase family associated with various cellular activities (AAA)

    2. NM_069460.3 → NP_501861.1  Mitochondrial sorting homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501861.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P54815
      Conserved Domains (3) summary
      smart00382
      Location:113 → 241
      AAA; ATPases associated with a variety of cellular activities
      pfam00004
      Location:117 → 246
      AAA; ATPase family associated with various cellular activities (AAA)
      cl09176
      Location:41 → 124
      FlgN; FlgN protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P54815.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous