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    K09A9.6 Aspartyl/asparaginy/proline hydroxylase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 181645, updated on 9-Dec-2024

    Summary

    Official Symbol
    K09A9.6
    Official Full Name
    Aspartyl/asparaginy/proline hydroxylase domain-containing protein
    Primary source
    WormBase:WBGene00010703
    Locus tag
    CELE_K09A9.6
    See related
    AllianceGenome:WB:WBGene00010703
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable peptidyl-aspartic acid 3-dioxygenase activity. Predicted to be involved in regulation of cytosolic calcium ion concentration. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Is expressed in anal depressor muscle; body wall musculature; nervous system; and reproductive system. Human ortholog(s) of this gene implicated in cholangiocarcinoma. Orthologous to human ASPH (aspartate beta-hydroxylase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See K09A9.6 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    15
    Sequence:
    Chromosome: X; NC_003284.9 (15577242..15586811)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Dynamin Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene putative NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial Neighboring gene ncRNA Neighboring gene ncRNA

    General gene information

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum  
    located_in membrane  

    General protein information

    Preferred Names
    Aspartyl/asparaginy/proline hydroxylase domain-containing protein
    NP_001123163.1
    • Confirmed by transcript evidence
    NP_510568.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      15577242..15586811
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078167.7NP_510568.1  Aspartyl/asparaginy/proline hydroxylase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510568.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EEF4
      Conserved Domains (3) summary
      TIGR02917
      Location:461634
      PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
      sd00006
      Location:597628
      TPR; TPR repeat [structural motif]
      pfam05118
      Location:703859
      Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase
    2. NM_001129691.5NP_001123163.1  Aspartyl/asparaginy/proline hydroxylase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001123163.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8WHT8
      Conserved Domains (3) summary
      TIGR02917
      Location:509682
      PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
      sd00006
      Location:645676
      TPR; TPR repeat [structural motif]
      pfam05118
      Location:751907
      Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase
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