lsl-1 C2H2-type domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: lsl-1
Official Full Name: C2H2-type domain-containing protein
Primary source: WormBase:WBGene00009937
Locus tag: CELE_F52F12.4
See related: AllianceGenome:WB:WBGene00009937
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in Z2; Z3; and germ cell. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See lsl-1 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 7

Sequence:: Chromosome: I; NC_003279.8 (9901279..9902929)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

STS1-181 (e-PCR)
- UniSTS:241671

F52F12.4 (e-PCR)
- UniSTS:306662

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: C2H2-type domain-containing protein

NP_492621.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

9901279..9902929

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_060220.7 → NP_492621.2 C2H2-type domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_492621.2

Status: REVIEWED

UniProtKB/TrEMBL

O02273

Conserved Domains (3) summary

COG5048
Location:26 → 160

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:39 → 59

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:93 → 115

zf-C2H2; Zinc finger, C2H2 type