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    C46H3.2 Caskin-2;SAM domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 3564865, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C46H3.2
    Official Full Name
    Caskin-2;SAM domain-containing protein
    Primary source
    WormBase:WBGene00016725
    Locus tag
    CELE_C46H3.2
    See related
    AllianceGenome:WB:WBGene00016725
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Orthologous to human CASKIN1 (CASK interacting protein 1) and CASKIN2 (CASK interacting protein 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C46H3.2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    19
    Sequence:
    Chromosome: X; NC_003284.9 (1211760..1230758, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene U1 small nuclear ribonucleoprotein C Neighboring gene Protein HAIKU1 Neighboring gene AMP-dependent synthetase/ligase domain-containing protein Neighboring gene Tetraspanin Neighboring gene DUF19 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article
    2. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
    3. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    4. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    Caskin-2;SAM domain-containing protein
    NP_001317737.1
    • Confirmed by transcript evidence
    NP_001317901.1
    • Confirmed by transcript evidence
    NP_001359896.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      1211760..1230758 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001373221.5 → NP_001359896.1  SAM domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86DC0
      Conserved Domains (2) summary
      cd09497
      Location:196 → 261
      SAM_caskin1,2_repeat1; SAM domain of caskin protein repeat 1
      cd09498
      Location:263 → 333
      SAM_caskin1,2_repeat2; SAM domain of caskin protein repeat 2

    2. NM_001330891.5 → NP_001317737.1  Caskin-2 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18662

    3. NM_001330892.4 → NP_001317901.1  SAM domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1C3NSM0
    Nucleotide Protein
    Heading Accession and Version

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