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    R119.5 Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 [ Caenorhabditis elegans ]

    Gene ID: 171631, updated on 9-Dec-2024

    Summary

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    Official Symbol
    R119.5
    Official Full Name
    Protein-L-isoaspartate O-methyltransferase domain-containing protein 1
    Primary source
    WormBase:WBGene00020090
    Locus tag
    CELE_R119.5
    See related
    AllianceGenome:WB:WBGene00020090
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein-L-isoaspartate (D-aspartate) O-methyltransferase activity. Predicted to be involved in protein modification process. Predicted to be active in cytoplasm. Orthologous to human PCMTD1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1) and PCMTD2 (protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See R119.5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    10
    Sequence:
    Chromosome: I; NC_003279.8 (388470..394415, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene RRM domain-containing protein Neighboring gene Aminopeptidase P N-terminal domain-containing protein Neighboring gene DeHydrogenases, Short chain Neighboring gene Prion-like (glutamine/asparagine-rich) domain bearing protein pqn-59 Neighboring gene Transcription initiation factor TFIID subunit 4 Neighboring gene ubiquitinyl hydrolase 1 Neighboring gene WD_REPEATS_REGION domain-containing protein Neighboring gene BTB domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein-L-isoaspartate (D-aspartate) O-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-L-isoaspartate (D-aspartate) O-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein modification process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Protein-L-isoaspartate O-methyltransferase domain-containing protein 1
    NP_001248847.1
    • Confirmed by transcript evidence
    NP_001248848.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      388470..394415 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001261919.2 → NP_001248848.1  Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001248848.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O61706
      Conserved Domains (2) summary
      TIGR00080
      Location:4 → 228
      pimt; protein-L-isoaspartate(D-aspartate) O-methyltransferase
      cl17173
      Location:11 → 212
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    2. NM_001261918.4 → NP_001248847.1  Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001248847.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H1ZUX5
      Conserved Domains (2) summary
      TIGR00080
      Location:4 → 228
      pimt; protein-L-isoaspartate(D-aspartate) O-methyltransferase
      cl17173
      Location:11 → 212
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    Nucleotide Protein
    Heading Accession and Version

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