U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    mboa-4 Membrane Bound O-Acyl transferase, MBOAT [ Caenorhabditis elegans ]

    Gene ID: 182414, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    mboa-4
    Official Full Name
    Membrane Bound O-Acyl transferase, MBOAT
    Primary source
    WormBase:WBGene00007446
    Locus tag
    CELE_C08F8.4
    See related
    AllianceGenome:WB:WBGene00007446
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable acyltransferase activity. Predicted to be involved in lipid modification. Predicted to be active in membrane. Orthologous to human MBOAT1 (membrane bound O-acyltransferase domain containing 1) and MBOAT2 (membrane bound O-acyltransferase domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See mboa-4 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    11
    Sequence:
    Chromosome: IV; NC_003282.8 (11157099..11159986, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ATP-dependent RNA helicase SUV3 homolog, mitochondrial Neighboring gene Uncharacterized protein Neighboring gene F-box domain-containing protein Neighboring gene F-box domain-containing protein Neighboring gene non-specific serine/threonine protein kinase Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Member of the membrane-bound O-acyltransferase (MBOAT) family encodes a lysophospholipid acyltransferase with broad substrate specificity. Matsuda S, et al. Genes Cells, 2008 Aug. PMID 18782225
    2. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables acyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid modification IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Membrane Bound O-Acyl transferase, MBOAT
    NP_001255543.1
    • Product from WormBase gene class mboa;
      Confirmed by transcript evidence
    NP_001255544.1
    • Product from WormBase gene class mboa;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      11157099..11159986 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268614.4 → NP_001255543.1  Membrane Bound O-Acyl transferase, MBOAT [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255543.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EEY2, H9G2W6
      Conserved Domains (1) summary
      cl00738
      Location:22 → 456
      MBOAT; MBOAT, membrane-bound O-acyltransferase family

    2. NM_001268615.3 → NP_001255544.1  Membrane Bound O-Acyl transferase, MBOAT [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255544.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EEY2, H9G2W5
      Conserved Domains (1) summary
      cl00738
      Location:22 → 471
      MBOAT; MBOAT, membrane-bound O-acyltransferase family
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous