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    W09C3.4 putative DNA-directed RNA polymerase III subunit RPC6 [ Caenorhabditis elegans ]

    Gene ID: 172081, updated on 9-Dec-2024

    Summary

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    Official Symbol
    W09C3.4
    Official Full Name
    putative DNA-directed RNA polymerase III subunit RPC6
    Primary source
    WormBase:WBGene00021112
    Locus tag
    CELE_W09C3.4
    See related
    AllianceGenome:WB:WBGene00021112
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human POLR3F (RNA polymerase III subunit F). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See W09C3.4 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (4704604..4705885)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Chromodomain and Helicase Domain protein Neighboring gene ncRNA Neighboring gene Methyltransferase FkbM domain-containing protein Neighboring gene Serine/threonine-protein phosphatase PP1-gamma

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in transcription by RNA polymerase III IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of DNA-directed RNA polymerase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of RNA polymerase III complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RNA polymerase III complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative DNA-directed RNA polymerase III subunit RPC6
    NP_491427.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      4704604..4705885
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059026.6 → NP_491427.1  putative DNA-directed RNA polymerase III subunit RPC6 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491427.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P91529
      Conserved Domains (1) summary
      cl02127
      Location:34 → 293
      RNA_pol_Rpc34; RNA polymerase Rpc34 subunit
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P91529.1

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