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    F43C11.8 RING-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 173590, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F43C11.8
    Official Full Name
    RING-type domain-containing protein
    Primary source
    WormBase:WBGene00018385
    Locus tag
    CELE_F43C11.8
    See related
    AllianceGenome:WB:WBGene00018385
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable zinc ion binding activity. Orthologous to human TRIM13 (tripartite motif containing 13) and TRIM59 (tripartite motif containing 59). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F43C11.8 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (2332520..2334338)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene RING-type domain-containing protein Neighboring gene RING-type domain-containing protein Neighboring gene RING-type domain-containing protein Neighboring gene Enhanced Nuclear RnaI (RNAi), T. Duchaine Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    RING-type domain-containing protein
    NP_494244.2
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      2332520..2334338
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_061843.4 → NP_494244.2  RING-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_494244.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U5C2
      Conserved Domains (3) summary
      cd00162
      Location:6 → 50
      RING_Ubox; modified RING-HC finger (C3HC3D-type) [structural motif]
      cd19774
      Location:88 → 137
      Bbox2_TRIM23_C-IX_rpt2; second B-box-type 2 zinc finger found in tripartite motif-containing protein 23 (TRIM23) and similar proteins
      cl17238
      Location:5 → 52
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    Nucleotide Protein
    Heading Accession and Version

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