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    rde-10 RNA interference defective protein 10 [ Caenorhabditis elegans ]

    Gene ID: 171923, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rde-10
    Official Full Name
    RNA interference defective protein 10
    Primary source
    WormBase:WBGene00021634
    Locus tag
    CELE_Y47G6A.4
    See related
    AllianceGenome:WB:WBGene00021634
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in regulation of miRNA-mediated gene silencing; regulation of translation; and regulatory ncRNA-mediated gene silencing. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See rde-10 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    11
    Sequence:
    Chromosome: I; NC_003279.8 (3547071..3552005)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Peptidase M14 carboxypeptidase A domain-containing protein;ShKT domain-containing protein Neighboring gene ncRNA Neighboring gene Tyrosine-protein kinase Neighboring gene Poly(U)-binding-splicing factor rnp-6 Neighboring gene DeHydrogenases, Short chain Neighboring gene ncRNA Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. New insights into siRNA amplification and RNAi. Zhang C, et al. RNA Biol, 2012 Aug. PMID 22858672, Free PMC Article
    2. The DEAD box helicase RDE-12 promotes amplification of RNAi in cytoplasmic foci in C. elegans. Yang H, et al. Curr Biol, 2014 Apr 14. PMID 24684930, Free PMC Article
    3. The RDE-10/RDE-11 complex triggers RNAi-induced mRNA degradation by association with target mRNA in C. elegans. Yang H, et al. Genes Dev, 2012 Apr 15. PMID 22508728, Free PMC Article
    4. Multiple small RNA pathways regulate the silencing of repeated and foreign genes in C. elegans. Fischer SE, et al. Genes Dev, 2013 Dec 15. PMID 24352423, Free PMC Article
    5. New Strains for Tissue-Specific RNAi Studies in Caenorhabditis elegans. Watts JS, et al. G3 (Bethesda), 2020 Nov 5. PMID 32943454, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in regulation of miRNA-mediated gene silencing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulatory ncRNA-mediated gene silencing IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    RNA interference defective protein 10
    NP_491178.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      3547071..3552005
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058777.7 → NP_491178.1  RNA interference defective protein 10 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491178.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9N3S2
      Conserved Domains (1) summary
      pfam13017
      Location:223 → 440
      Maelstrom; piRNA pathway germ-plasm component
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9N3S2.1

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