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    K11G12.6 Lipase maturation factor [ Caenorhabditis elegans ]

    Gene ID: 180941, updated on 9-Dec-2024

    Summary

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    Official Symbol
    K11G12.6
    Official Full Name
    Lipase maturation factor
    Primary source
    WormBase:WBGene00019657
    Locus tag
    CELE_K11G12.6
    See related
    AllianceGenome:WB:WBGene00019657
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in protein maturation. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human LMF2 (lipase maturation factor 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See K11G12.6 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    11
    Sequence:
    Chromosome: X; NC_003284.9 (6725689..6729657, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene NRAMP-like transporter smf-1 Neighboring gene Mitochondrial dicarboxylate carrier Neighboring gene Glycosyl hydrolase family 63 C-terminal domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in protein maturation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein maturation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Lipase maturation factor
    NP_001041273.1
    • Confirmed by transcript evidence
    NP_001041274.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      6725689..6729657 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047809.5 → NP_001041274.2  Lipase maturation factor [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041274.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2L6Y0
      Conserved Domains (1) summary
      pfam06762
      Location:127 → 551
      LMF1; Lipase maturation factor

    2. NM_001047808.4 → NP_001041273.1  Lipase maturation factor [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041273.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21435
      Conserved Domains (1) summary
      pfam06762
      Location:6 → 430
      LMF1; Lipase maturation factor
    Nucleotide Protein
    Heading Accession and Version

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