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    dsbn-1 Dysbindin protein homolog [ Caenorhabditis elegans ]

    Gene ID: 172849, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dsbn-1
    Official Full Name
    Dysbindin protein homolog
    Primary source
    WormBase:WBGene00013697
    Locus tag
    CELE_Y106G6A.5
    See related
    AllianceGenome:WB:WBGene00013697
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in endosomal transport. Predicted to be part of BLOC-1 complex. Used to study Hermansky-Pudlak syndrome. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See dsbn-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (9934637..9936022, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Methyltranfer_dom domain-containing protein Neighboring gene START domain-containing protein;Steroidogenic acute regulatory-like protein 1 Neighboring gene BAR domain-containing protein Neighboring gene MRG domain-containing protein Neighboring gene Protein kinase domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. C. elegans BLOC-1 functions in trafficking to lysosome-related gut granules. Hermann GJ, et al. PLoS One, 2012. PMID 22916203, Free PMC Article
    2. Prefoldin 6 mediates longevity response from heat shock factor 1 to FOXO in C. elegans. Son HG, et al. Genes Dev, 2018 Dec 1. PMID 30478249, Free PMC Article
    3. Axon guidance genes identified in a large-scale RNAi screen using the RNAi-hypersensitive Caenorhabditis elegans strain nre-1(hd20) lin-15b(hd126). Schmitz C, et al. Proc Natl Acad Sci U S A, 2007 Jan 16. PMID 17213328, Free PMC Article
    4. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    5. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endosomal transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of BLOC-1 complex TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Dysbindin protein homolog
    NP_001122534.1
    • Confirmed by transcript evidence
    NP_492628.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      9934637..9936022 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001129062.5 → NP_001122534.1  Dysbindin protein homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122534.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A5HW99

    2. NM_060227.4 → NP_492628.1  Dysbindin protein homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492628.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9XWQ1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XWQ1.1

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