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    ska-1 SKA complex subunit 1 [ Caenorhabditis elegans ]

    Gene ID: 190930, updated on 9-Dec-2024

    Summary

    Official Symbol
    ska-1
    Official Full Name
    SKA complex subunit 1
    Primary source
    WormBase:WBGene00013725
    Locus tag
    CELE_Y106G6H.15
    See related
    AllianceGenome:WB:WBGene00013725
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables microtubule binding activity. Predicted to be involved in chromosome segregation; mitotic cell cycle; and regulation of microtubule polymerization or depolymerization. Located in kinetochore and mitotic spindle. Orthologous to human SKA1 (spindle and kinetochore associated complex subunit 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See ska-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (10473513..10474435, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Reverse transcriptase domain-containing protein Neighboring gene Osteoclast-stimulating factor 1 Neighboring gene Dynein light chain Neighboring gene C2H2-type domain-containing protein Neighboring gene BRCT domain-containing protein

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables microtubule binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chromosome segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of microtubule polymerization or depolymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in kinetochore IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in kinetochore IEA
    Inferred from Electronic Annotation
    more info
     
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in mitotic spindle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitotic spindle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of outer kinetochore IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in spindle IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in spindle microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    SKA complex subunit 1
    NP_492739.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      10473513..10474435 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060338.7NP_492739.1  SKA complex subunit 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492739.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9XWS0
      Conserved Domains (1) summary
      pfam07160
      Location:19224
      DUF1395; Protein of unknown function (DUF1395)