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    rfip-2 FIP-RBD domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 173462, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rfip-2
    Official Full Name
    FIP-RBD domain-containing protein
    Primary source
    WormBase:WBGene00021456
    Locus tag
    CELE_Y39F10B.1
    See related
    AllianceGenome:WB:WBGene00021456
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable small GTPase binding activity. Predicted to be involved in regulated exocytosis. Predicted to be active in intracellular membrane-bounded organelle. Orthologous to several human genes including RAB11FIP1 (RAB11 family interacting protein 1) and RAB11FIP5 (RAB11 family interacting protein 5). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See rfip-2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    8
    Sequence:
    Chromosome: II; NC_003280.10 (723788..732513)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Death domain-containing protein Neighboring gene WD_REPEATS_REGION domain-containing protein Neighboring gene pseudo Neighboring gene F-box C protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Caenorhabditis elegans gene mfap-1 encodes a nuclear protein that affects alternative splicing. Ma L, et al. PLoS Genet, 2012. PMID 22829783, Free PMC Article
    2. Loss of heat shock factor initiates intracellular lipid surveillance by actin destabilization. Watterson A, et al. Cell Rep, 2022 Oct 18. PMID 36261024, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulated exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    FIP-RBD domain-containing protein
    NP_493798.2
    • Confirmed by transcript evidence
    NP_872031.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      723788..732513
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_061397.5 → NP_493798.2  FIP-RBD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493798.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B2FD95
      Conserved Domains (1) summary
      cl14603
      Location:62 → 172
      C2; C2 domain

    2. NM_182231.7 → NP_872031.2  FIP-RBD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_872031.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B2FD96
      Conserved Domains (1) summary
      cl14603
      Location:13 → 123
      C2; C2 domain
    Nucleotide Protein
    Heading Accession and Version

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