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    Y55F3AR.2 Thioredoxin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176929, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y55F3AR.2
    Official Full Name
    Thioredoxin domain-containing protein
    Primary source
    WormBase:WBGene00021933
    Locus tag
    CELE_Y55F3AR.2
    See related
    AllianceGenome:WB:WBGene00021933
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein-disulfide reductase activity. Predicted to be located in membrane. Predicted to be active in cytosol. Orthologous to human TXNDC8 (thioredoxin domain containing 8). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y55F3AR.2 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (1094541..1097342)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene CCT-theta;T-complex protein 1 subunit theta Neighboring gene ncRNA Neighboring gene Cytochrome OXidase assembly protein Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein-disulfide reductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Thioredoxin domain-containing protein
    NP_500036.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      1094541..1097342
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067635.5 → NP_500036.2  Thioredoxin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500036.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N357
      Conserved Domains (2) summary
      cd02947
      Location:10 → 103
      TRX_family; TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox ...
      pfam15378
      Location:157 → 212
      DUF4605; Domain of unknown function (DUF4605)
    Nucleotide Protein
    Heading Accession and Version

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