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    pmp-5 ABC transmembrane type-1 domain-containing protein;ABC transporter domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179056, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pmp-5
    Official Full Name
    ABC transmembrane type-1 domain-containing protein;ABC transporter domain-containing protein
    Primary source
    WormBase:WBGene00004062
    Locus tag
    CELE_T10H9.5
    See related
    AllianceGenome:WB:WBGene00004062
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ATP binding activity; ATPase-coupled transmembrane transporter activity; and long-chain fatty acid transmembrane transporter activity. Predicted to be involved in fatty acid catabolic process; long-chain fatty acid import into peroxisome; and peroxisome organization. Predicted to be located in membrane. Predicted to be active in peroxisomal membrane. Is expressed in hypodermis and intestine. Orthologous to human ABCD4 (ATP binding cassette subfamily D member 4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See pmp-5 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    13
    Sequence:
    Chromosome: V; NC_003283.11 (6662191..6665813, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Seven TM Receptor Neighboring gene Carboxylic ester hydrolase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The effects of nested miRNAs and their host genes on immune defense against Bacillus thuringiensis infection in Caenorhabditis elegans. Zárate-Potes A, et al. Dev Comp Immunol, 2021 Oct. PMID 34051205
    2. Role of NH2-terminal hydrophobic motif in the subcellular localization of ATP-binding cassette protein subfamily D: common features in eukaryotic organisms. Lee A, et al. Biochem Biophys Res Commun, 2014 Oct 24. PMID 25301552
    3. Caenorhabditis elegans methionine/S-adenosylmethionine cycle activity is sensed and adjusted by a nuclear hormone receptor. Giese GE, et al. Elife, 2020 Oct 5. PMID 33016879, Free PMC Article
    4. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    5. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables long-chain fatty acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in long-chain fatty acid import into peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in peroxisome organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in very long-chain fatty acid catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in peroxisomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ABC transmembrane type-1 domain-containing protein;ABC transporter domain-containing protein
    NP_001024131.1
    • Confirmed by transcript evidence
    NP_504689.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      6662191..6665813 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072288.7 → NP_504689.1  ABC transporter domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504689.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L034
      Conserved Domains (1) summary
      COG4178
      Location:33 → 582
      YddA; ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]

    2. NM_001028960.6 → NP_001024131.1  ABC transmembrane type-1 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024131.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L035
      Conserved Domains (1) summary
      COG4178
      Location:33 → 561
      YddA; ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]
    Nucleotide Protein
    Heading Accession and Version

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