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    • Showing Current items.

    cut-1 Cuticlin-1 [ Caenorhabditis elegans ]

    Gene ID: 174720, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cut-1
    Official Full Name
    Cuticlin-1
    Primary source
    WormBase:WBGene00000851
    Locus tag
    CELE_C47G2.1
    See related
    AllianceGenome:WB:WBGene00000851
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of cuticle. Located in collagen and cuticulin-based cuticle extracellular matrix. Is expressed in cuticle and seam cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cut-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003280.10 (11269122..11271660)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. cut-1-like genes are present in the filarial nematodes, Brugia pahangi and Brugia malayi, and, as in other nematodes, code for components of the cuticle. Lewis E, et al. Mol Biochem Parasitol, 1999 Jun 25. PMID 10413052
    2. Immuno-cross-reactivity of CUT-1 and cuticlin epitopes between ascaris lumbricoides, Caenorhabditis elegans, and Heterorhabditis. Favre R, et al. J Struct Biol, 1998 Sep. PMID 9774538
    3. cut-1-like genes of Ascaris lumbricoides. Timinouni M, et al. Gene, 1997 Jul 1. PMID 9249070
    4. Forms and functions of nematode surfaces. Maizels RM, et al. Exp Parasitol, 1993 Nov. PMID 8224093
    5. Ultrastructural immuno-localization of CUT-1 and CUT-2 antigenic sites in the cuticles of the nematode Caenorhabditis elegans. Ristoratore F, et al. J Submicrosc Cytol Pathol, 1994 Jul. PMID 8087805

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The Zona Pellucida domain containing proteins, CUT-1, CUT-3 and CUT-5, play essential roles in the development of the larval alae in Caenorhabditis elegans.
      Title: The Zona Pellucida domain containing proteins, CUT-1, CUT-3 and CUT-5, play essential roles in the development of the larval alae in Caenorhabditis elegans.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of cuticle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in collagen and cuticulin-based cuticle extracellular matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cuticlin-1
    NP_496410.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      11269122..11271660
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064009.4 → NP_496410.1  Cuticlin-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496410.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q03755, Q18693
      Conserved Domains (2) summary
      smart00241
      Location:32 → 271
      ZP; Zona pellucida (ZP) domain
      pfam00100
      Location:171 → 271
      Zona_pellucida; Zona pellucida-like domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03755.2

    Gene LinkOut

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