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    gst-32 Glutathione S-transferase [ Caenorhabditis elegans ]

    Gene ID: 190230, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gst-32
    Official Full Name
    Glutathione S-transferase
    Primary source
    WormBase:WBGene00001780
    Locus tag
    CELE_Y53F4B.37
    See related
    AllianceGenome:WB:WBGene00001780
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable glutathione transferase activity. Involved in response to reactive oxygen species. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See gst-32 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003280.10 (15177345..15178594, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Glutathione S-transferase Neighboring gene Wsv310-like protein Neighboring gene Glutathione S-Transferase Neighboring gene Glutathione transferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The glutathione reductase GSR-1 determines stress tolerance and longevity in Caenorhabditis elegans. Lüersen K, et al. PLoS One, 2013. PMID 23593298, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables glutathione transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glutathione transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glutathione metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in response to reactive oxygen species IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Glutathione S-transferase
    NP_497123.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      15177345..15178594 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064722.3 → NP_497123.2  Glutathione S-transferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497123.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9NA96
      Conserved Domains (3) summary
      PTZ00057
      Location:6 → 208
      PTZ00057; glutathione s-transferase; Provisional
      cd03192
      Location:85 → 191
      GST_C_Sigma_like; C-terminal, alpha helical domain of Class Sigma-like Glutathione S-transferases
      cd03039
      Location:4 → 74
      GST_N_Sigma_like; GST_N family, Class Sigma_like; composed of GSTs belonging to class Sigma and similar proteins, including GSTs from class Mu, Pi and Alpha. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of ...
    Nucleotide Protein
    Heading Accession and Version

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