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    F54B3.1 Protein SZT2 [ Caenorhabditis elegans ]

    Gene ID: 174591, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F54B3.1
    Official Full Name
    Protein SZT2
    Primary source
    WormBase:WBGene00010013
    Locus tag
    CELE_F54B3.1
    See related
    AllianceGenome:WB:WBGene00010013
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be active in peroxisome. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 18. Orthologous to human SZT2 (SZT2 subunit of KICSTOR complex). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F54B3.1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    20
    Sequence:
    Chromosome: II; NC_003280.10 (10251266..10268213)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Nuclear exosome regulator NRDE2 Neighboring gene ATPase family AAA domain-containing protein 3 Neighboring gene Secreted protein Neighboring gene Neuropeptide-Like Protein Neighboring gene Secreted protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein SZT2
    NP_001122614.2
    • Confirmed by transcript evidence
    NP_496211.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      10251266..10268213
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001129142.5 → NP_001122614.2  Protein SZT2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122614.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A5Z2S3

    2. NM_063810.5 → NP_496211.2  Protein SZT2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496211.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O62263
    Nucleotide Protein
    Heading Accession and Version

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