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    yop-1 Receptor expression-enhancing protein [ Caenorhabditis elegans ]

    Gene ID: 171835, updated on 9-Dec-2024

    Summary

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    Official Symbol
    yop-1
    Official Full Name
    Receptor expression-enhancing protein
    Primary source
    WormBase:WBGene00022127
    Locus tag
    CELE_Y71F9B.3
    See related
    AllianceGenome:WB:WBGene00022127
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Located in cortical endoplasmic reticulum. Is expressed in several structures, including excretory cell; nervous system; non-striated muscle; rectal gland cell; and reproductive system. Human ortholog(s) of this gene implicated in retinitis pigmentosa 77. Orthologous to human REEP5 (receptor accessory protein 5) and REEP6 (receptor accessory protein 6). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See yop-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003279.8 (2730004..2731453)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Cyclin N-terminal domain-containing protein Neighboring gene putative small nuclear ribonucleoprotein G Neighboring gene Phosphatidate cytidylyltransferase, mitochondrial Neighboring gene eLRR (extracellular Leucine-Rich Repeat) ONly Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cytoplasmic streaming drifts the polarity cue and enables posteriorization of the Caenorhabditis elegans zygote at the side opposite of sperm entry. Kimura K, et al. Mol Biol Cell, 2020 Jul 21. PMID 32459552, Free PMC Article
    2. A role for Rab5 in structuring the endoplasmic reticulum. Audhya A, et al. J Cell Biol, 2007 Jul 2. PMID 17591921, Free PMC Article
    3. A pathway for phagosome maturation during engulfment of apoptotic cells. Kinchen JM, et al. Nat Cell Biol, 2008 May. PMID 18425118, Free PMC Article
    4. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    5. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in cortical endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    Receptor expression-enhancing protein
    NP_491033.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      2730004..2731453
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058632.8 → NP_491033.1  Receptor expression-enhancing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491033.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N4G8
      Conserved Domains (1) summary
      pfam03134
      Location:60 → 147
      TB2_DP1_HVA22; TB2/DP1, HVA22 family
    Nucleotide Protein
    Heading Accession and Version

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