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    R07E4.1 Fibronectin type-III domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180863, updated on 9-Dec-2024

    Summary

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    Official Symbol
    R07E4.1
    Official Full Name
    Fibronectin type-III domain-containing protein
    Primary source
    WormBase:WBGene00019935
    Locus tag
    CELE_R07E4.1
    See related
    AllianceGenome:WB:WBGene00019935
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in establishment of mitotic spindle orientation and regulation of establishment of bipolar cell polarity. Predicted to be active in spindle. Orthologous to human ANKFN1 (ankyrin repeat and fibronectin type III domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See R07E4.1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    23
    Sequence:
    Chromosome: X; NC_003284.9 (5959115..5970273)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Cytochrome b-c1 complex subunit 8 Neighboring gene ncRNA Neighboring gene cAMP-dependent protein kinase regulatory subunit Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in establishment of mitotic spindle orientation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of establishment of bipolar cell polarity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in spindle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Fibronectin type-III domain-containing protein
    NP_001361971.1
    • Confirmed by transcript evidence
    NP_001361972.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      5959115..5970273
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001375040.2 → NP_001361971.1  Fibronectin type-III domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZC1
      Conserved Domains (2) summary
      cd00063
      Location:327 → 409
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl28922
      Location:1026 → 1119
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    2. NM_001375041.2 → NP_001361972.1  Fibronectin type-III domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5WRT5
      Conserved Domains (2) summary
      cd00063
      Location:228 → 310
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl28922
      Location:927 → 1020
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    Nucleotide Protein
    Heading Accession and Version

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