pinn-4 Peptidyl-prolyl cis-trans isomerase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: pinn-4
Official Full Name: Peptidyl-prolyl cis-trans isomerase
Primary source: WormBase:WBGene00012996
Locus tag: CELE_Y48C3A.16
See related: AllianceGenome:WB:WBGene00012996
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable DNA binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in rRNA processing. Located in plasma membrane. Is expressed in several structures, including head; hypodermis; intestine; pharynx; and tail. Orthologous to human PIN4 (peptidylprolyl cis/trans isomerase, NIMA-interacting 4). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See pinn-4 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 2

Sequence:: Chromosome: II; NC_003280.10 (13402980..13404614)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

this work presents a first attempt to characterize the Caenorhabditis elegans parvulins.
Title: The Caenorhabditis elegans parvulin gene subfamily and their expression under cold or heat stress along with the fkb subfamily.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y48C3A.s (e-PCR)
- UniSTS:323947

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables peptidyl-prolyl cis-trans isomerase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in rRNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	HDA more info	PubMed

General protein information

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Preferred Names: Peptidyl-prolyl cis-trans isomerase

NP_001370079.1

Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

13402980..13404614

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001383980.2 → NP_001370079.1 Peptidyl-prolyl cis-trans isomerase [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

Q9NAF9

Conserved Domains (1) summary

cl29122
Location:27 → 126

Rotamase_2; PPIC-type PPIASE domain