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    lon-8 Protein lon-8 [ Caenorhabditis elegans ]

    Gene ID: 190397, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lon-8
    Official Full Name
    Protein lon-8
    Primary source
    WormBase:WBGene00013352
    Locus tag
    CELE_Y59A8B.20
    See related
    AllianceGenome:WB:WBGene00013352
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in nematode male tail tip morphogenesis and regulation of growth. Predicted to be located in extracellular space. Is expressed in hyp4; hyp7 syncytium; and intestine. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See lon-8 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    4
    Sequence:
    Chromosome: V; NC_003283.11 (17995347..18001368, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene PX domain-containing protein;Sorting nexin/Vps5-like C-terminal domain-containing protein Neighboring gene MFS domain-containing protein Neighboring gene DUF148 domain-containing protein Neighboring gene DUF148 domain-containing protein;Glycine-rich cell wall structural protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of Caenorhabditis elegans body size and male tail development by the novel gene lon-8. Soete G, et al. BMC Dev Biol, 2007 Mar 20. PMID 17374156, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The novel gene lon-8 encodes a secreted product of the hypodermis that controls body size and male ray morphology in C. elegans
      Title: Regulation of Caenorhabditis elegans body size and male tail development by the novel gene lon-8.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in negative regulation of multicellular organism growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nematode male tail tip morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Protein lon-8
    NP_507520.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      17995347..18001368 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_075119.5 → NP_507520.3  Protein lon-8 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_507520.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      G5EGH7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    G5EGH7.1

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