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    ndx-6 Putative nudix hydrolase 6 [ Caenorhabditis elegans ]

    Gene ID: 173916, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ndx-6
    Official Full Name
    Putative nudix hydrolase 6
    Primary source
    WormBase:WBGene00003583
    Locus tag
    CELE_EEED8.8
    See related
    AllianceGenome:WB:WBGene00003583
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ADP-ribose diphosphatase activity and metal ion binding activity. Orthologous to human NUDT9 (nudix hydrolase 9). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ndx-6 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003280.10 (5388829..5389881, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Protein kinase C-like 3 Neighboring gene Cytosolic carboxypeptidase 6 Neighboring gene putative splicing factor, arginine/serine-rich 4 Neighboring gene BRCA1-associated protein homolog 2 Neighboring gene Serine/threonine-protein kinase pink-1, mitochondrial

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Caenorhabditis elegans Y87G2A.14 Nudix hydrolase is a peroxisomal coenzyme A diphosphatase. AbdelRaheim SR, et al. BMC Biochem, 2002 Mar 27. PMID 11943069, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ADP-ribose diphosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Putative nudix hydrolase 6
    NP_495015.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      5388829..5389881 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062614.6 → NP_495015.1  Putative nudix hydrolase 6 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495015.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q09297
      Conserved Domains (1) summary
      cl00447
      Location:95 → 258
      Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q09297.2

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