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    dpy-26 Condensin complex subunit dpy-26 [ Caenorhabditis elegans ]

    Gene ID: 178196, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dpy-26
    Official Full Name
    Condensin complex subunit dpy-26
    Primary source
    WormBase:WBGene00001085
    Locus tag
    CELE_C25G4.5
    See related
    AllianceGenome:WB:WBGene00001085
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in dosage compensation by hypoactivation of X chromosome; meiotic sister chromatid segregation; and mitotic sister chromatid segregation. Located in condensed nuclear chromosome. Part of dosage compensation complex. Is expressed in several structures, including pharynx and vulva. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See dpy-26 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    10
    Sequence:
    Chromosome: IV; NC_003282.8 (12445801..12451335, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Esterase C25G4.2 Neighboring gene ncRNA Neighboring gene Ribosome-binding factor A Neighboring gene Transcription regulator spe-44 Neighboring gene PDZ domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sex determination: a hypothesis based on noncoding DNA. Chandra HS. Proc Natl Acad Sci U S A, 1985 Feb. PMID 3919386, Free PMC Article
    2. The Caenorhabditis elegans dosage compensation machinery is recruited to X chromosome DNA attached to an autosome. Lieb JD, et al. Genetics, 2000 Dec. PMID 11102361, Free PMC Article
    3. MIX-1: an essential component of the C. elegans mitotic machinery executes X chromosome dosage compensation. Lieb JD, et al. Cell, 1998 Jan 23. PMID 9458050
    4. Genetic analysis of X-chromosome dosage compensation in Caenorhabditis elegans. Meneely PM, et al. Genetics, 1987 Sep. PMID 3666440, Free PMC Article
    5. Condensin and the spindle midzone prevent cytokinesis failure induced by chromatin bridges in C. elegans embryos. Bembenek JN, et al. Curr Biol, 2013 Jun 3. PMID 23684975, Free PMC Article

    See all (63) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chromosome condensation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in dosage compensation by hypoactivation of X chromosome IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in meiotic chromosome segregation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in meiotic sister chromatid segregation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitotic sister chromatid segregation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in condensed nuclear chromosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of dosage compensation complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in nuclear chromosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Condensin complex subunit dpy-26
    NP_502378.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      12445801..12451335 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069977.9 → NP_502378.1  Condensin complex subunit dpy-26 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502378.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      G5EGE9
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    G5EGE9.1

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