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    acs-6 fatty Acid CoA Synthetase family [ Caenorhabditis elegans ]

    Gene ID: 174156, updated on 9-Dec-2024

    Summary

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    Official Symbol
    acs-6
    Official Full Name
    fatty Acid CoA Synthetase family
    Primary source
    WormBase:WBGene00022849
    Locus tag
    CELE_ZK1127.2
    See related
    AllianceGenome:WB:WBGene00022849
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable CoA-ligase activity. Predicted to be located in peroxisome. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See acs-6 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    9
    Sequence:
    Chromosome: II; NC_003280.10 (7062030..7064777)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Protein BCCIP homolog Neighboring gene Uncharacterized protein Neighboring gene Putative cystathionine gamma-lyase 2 Neighboring gene MutS protein homolog him-14 Neighboring gene Nanos-type domain-containing protein Neighboring gene Lysine--tRNA ligase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Di(2-ethylhexyl) phthalate and diethyl phthalate disrupt lipid metabolism, reduce fecundity and shortens lifespan of Caenorhabditis elegans. Pradhan A, et al. Chemosphere, 2018 Jan. PMID 29020644
    2. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables CoA-ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    fatty Acid CoA Synthetase family
    NP_495450.1
    • Product from WormBase gene class acs;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      7062030..7064777
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063049.5 → NP_495450.1  fatty Acid CoA Synthetase family [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495450.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23404
      Conserved Domains (2) summary
      cd05911
      Location:37 → 532
      Firefly_Luc_like; Firefly luciferase of light emitting insects and 4-Coumarate-CoA Ligase (4CL)
      COG0318
      Location:15 → 541
      CaiC; Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]
    Nucleotide Protein
    Heading Accession and Version

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