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    W04B5.5 Protein kinase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 175360, updated on 9-Dec-2024

    Summary

    Official Symbol
    W04B5.5
    Official Full Name
    Protein kinase domain-containing protein
    Primary source
    WormBase:WBGene00021022
    Locus tag
    CELE_W04B5.5
    See related
    AllianceGenome:WB:WBGene00021022
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Is expressed in body wall musculature; intestine; and nervous system. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human PDPK1 (3-phosphoinositide dependent protein kinase 1) and PDPK2P (3-phosphoinositide dependent protein kinase 2, pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See W04B5.5 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    7
    Sequence:
    Chromosome: III; NC_003281.10 (2411081..2418209, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Cyclin-C Neighboring gene ncRNA Neighboring gene Sterol 4-C-methyltransferase strm-1 Neighboring gene 39S ribosomal protein L30, mitochondrial Neighboring gene ncRNA Neighboring gene Galectin Neighboring gene pseudo

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Protein kinase domain-containing protein
    NP_497551.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      2411081..2418209 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065150.7NP_497551.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497551.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9UA62
      Conserved Domains (1) summary
      cl21453
      Location:25303
      PKc_like; Protein Kinases, catalytic domain