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    C55A6.7 DeHydrogenases, Short chain [ Caenorhabditis elegans ]

    Gene ID: 183836, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C55A6.7
    Official Full Name
    DeHydrogenases, Short chain
    Primary source
    WormBase:WBGene00008336
    Locus tag
    CELE_C55A6.7
    See related
    AllianceGenome:WB:WBGene00008336
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable oxidoreductase activity. Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be active in cytoplasm. Orthologous to human CBR3 (carbonyl reductase 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C55A6.7 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    3
    Sequence:
    Chromosome: V; NC_003283.11 (11519334..11520530, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene DeHydrogenases, Short chain Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene RNA polymerase II-associated factor 1 homolog Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Shapira M, et al. Proc Natl Acad Sci U S A, 2006 Sep 19. PMID 16968778, Free PMC Article
    2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response to Gram-negative bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in innate immune response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    DeHydrogenases, Short chain
    NP_505924.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      11519334..11520530 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073523.6 → NP_505924.1  DeHydrogenases, Short chain [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505924.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      P90781
      Conserved Domains (2) summary
      cd05325
      Location:6 → 250
      carb_red_sniffer_like_SDR_c; carbonyl reductase sniffer-like, classical (c) SDRs
      pfam00106
      Location:4 → 216
      adh_short; short chain dehydrogenase
    Nucleotide Protein
    Heading Accession and Version

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