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    ZK892.4 CaiB/baiF CoA-transferase family protein ZK892.4 [ Caenorhabditis elegans ]

    Gene ID: 174559, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ZK892.4
    Official Full Name
    CaiB/baiF CoA-transferase family protein ZK892.4
    Primary source
    WormBase:WBGene00014128
    Locus tag
    CELE_ZK892.4
    See related
    AllianceGenome:WB:WBGene00014128
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable alpha-methylacyl-CoA racemase activity. Predicted to be involved in bile acid metabolic process. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in alpha-methylacyl-CoA racemase deficiency; congenital bile acid synthesis defect 4; and urinary bladder cancer. Orthologous to human AMACR (alpha-methylacyl-CoA racemase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ZK892.4 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    7
    Sequence:
    Chromosome: II; NC_003280.10 (10006566..10008138)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene pseudo Neighboring gene Transmembrane protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Galectin;Galectin domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables alpha-methylacyl-CoA racemase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in bile acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    CaiB/baiF CoA-transferase family protein ZK892.4
    NP_496163.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      10006566..10008138
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063762.5 → NP_496163.2  CaiB/baiF CoA-transferase family protein ZK892.4 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496163.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q09618
      Conserved Domains (1) summary
      cl19215
      Location:5 → 313
      CoA_transf_3; CoA-transferase family III
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q09618.3

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