zipt-16 Zrt (ZRT), Irt- (IRT-) like Protein Transporter [Caenorhabditis elegans] - Gene

Summary

Official Symbol: zipt-16
Official Full Name: Zrt (ZRT), Irt- (IRT-) like Protein Transporter
Primary source: WormBase:WBGene00006486
Locus tag: CELE_T11F9.2
See related: AllianceGenome:WB:WBGene00006486
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable monoatomic cation:bicarbonate symporter activity and zinc ion transmembrane transporter activity. Predicted to be involved in intracellular monoatomic cation homeostasis and zinc ion import across plasma membrane. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in nervous system and tail. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIn. Orthologous to human SLC39A8 (solute carrier family 39 member 8). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

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Zinc transporters maintain longevity by influencing insulin/IGF-1 activity in Caenorhabditis elegans.
Title: Zinc transporters maintain longevity by influencing insulin/IGF-1 activity in Caenorhabditis elegans.

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Function	Evidence Code	Pubs
enables metal ion transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables monoatomic cation:bicarbonate symporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables zinc ion transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in bicarbonate transport	IEA Inferred from Electronic Annotation more info
involved_in intracellular monoatomic cation homeostasis	IBA Inferred from Biological aspect of Ancestor more info
involved_in metal ion transport	IEA Inferred from Electronic Annotation more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in zinc ion import across plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

NP_001369943.1

NP_001370142.1

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The following sections contain reference sequences that belong to a specific genome build. Explain