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    F30H5.3 BPTI/Kunitz inhibitor domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 175207, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F30H5.3
    Official Full Name
    BPTI/Kunitz inhibitor domain-containing protein
    Primary source
    WormBase:WBGene00017937
    Locus tag
    CELE_F30H5.3
    See related
    AllianceGenome:WB:WBGene00017937
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable serine-type endopeptidase inhibitor activity. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F30H5.3 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    9
    Sequence:
    Chromosome: III; NC_003281.10 (505241..512217, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene UNC-45/Cro1/She4 central domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene BPTI/Kunitz inhibitor domain-containing protein Neighboring gene DUF19 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Tewari M, et al. Mol Cell, 2004 Feb 27. PMID 14992718
    2. Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways. Duchaine TF, et al. Cell, 2006 Jan 27. PMID 16439208
    3. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article
    4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    BPTI/Kunitz inhibitor domain-containing protein
    NP_497206.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      505241..512217 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064805.4 → NP_497206.1  BPTI/Kunitz inhibitor domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497206.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q09983
      Conserved Domains (4) summary
      smart00131
      Location:481 → 516
      KU; BPTI/Kunitz family of serine protease inhibitors
      pfam00014
      Location:562 → 613
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam01683
      Location:1267 → 1318
      EB; EB module
      pfam14625
      Location:1467 → 1511
      Lustrin_cystein; Lustrin, cysteine-rich repeated domain
    Nucleotide Protein
    Heading Accession and Version

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