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    ceh-19 Homeobox protein ceh-19 [ Caenorhabditis elegans ]

    Gene ID: 177590, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ceh-19
    Official Full Name
    Homeobox protein ceh-19
    Primary source
    WormBase:WBGene00000442
    Locus tag
    CELE_F20D12.6
    See related
    AllianceGenome:WB:WBGene00000442
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in intestine and neurons. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ceh-19 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    5
    Sequence:
    Chromosome: IV; NC_003282.8 (7953500..7955949, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Centromere/kinetochore protein zw10 homolog Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene PCI domain-containing protein Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene Piwi domain-containing protein Neighboring gene Tyrosine-protein phosphatase domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Caenorhabditis elegans homeobox gene ceh-19 is required for MC motorneuron function. Feng H, et al. Genesis, 2013 Mar. PMID 23315936, Free PMC Article
    2. Identification of a homeobox-containing gene located between lin-45 and unc-24 on chromosome IV in the nematode Caenorhabditis elegans. Naito M, et al. Nucleic Acids Res, 1992 Jun 25. PMID 1352400, Free PMC Article
    3. Codon usage in Caenorhabditis elegans: delineation of translational selection and mutational biases. Stenico M, et al. Nucleic Acids Res, 1994 Jul 11. PMID 8041603, Free PMC Article
    4. Unique homeobox codes delineate all the neuron classes of C. elegans. Reilly MB, et al. Nature, 2020 Aug. PMID 32814896, Free PMC Article
    5. A 4D single-cell protein atlas of transcription factors delineates spatiotemporal patterning during embryogenesis. Ma X, et al. Nat Methods, 2021 Aug. PMID 34312566

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CEH-19 is required for activation for flp-2 gene and mc motorneuron function.
      Title: The Caenorhabditis elegans homeobox gene ceh-19 is required for MC motorneuron function.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Homeobox protein ceh-19
    NP_001023141.1
    • Confirmed by transcript evidence
    NP_001023142.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      7953500..7955949 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001027971.6 → NP_001023142.1  Homeobox protein ceh-19 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001023142.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P26797, Q19644
      Conserved Domains (1) summary
      pfam00046
      Location:97 → 150
      Homeobox; Homeobox domain

    2. NM_001027970.4 → NP_001023141.1  Homeobox protein ceh-19 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001023141.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P26797
      Conserved Domains (1) summary
      pfam00046
      Location:20 → 73
      Homeobox; Homeobox domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P26797.2

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